A variety of chemicals present in cigarette smoke enhances transepidermal water loss, upregulation of matrix metalloproteases (MMP) MMP-1 and MMP-3 implicated in collagen and elastic fibers degradation which, together with induced oxidative stress, contribute to the degeneration of connective tissue and premature aging in the skin [61]
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Babies and children who breathe secondhand smoke are sick more often with bronchitis, pneumonia, and ear infections than those that are not exposed to secondhand smoke
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Nicotine Level: Generally higher due to the use of stronger leaves and slower combustion
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